SAMe

S-Adenosyl-L-Methionine is a naturally occurring compound involved in critical methylation processes in the body, supporting mood, joint health, liver function, and cellular regeneration
Methylation Compounds Methyl Donors Research: Extensive

Scientific Name

S-Adenosyl-L-Methionine

Also Known As

SAMe SAM-e S-Adenosyl-L-Methionine S-Adenosylmethionine AdoMet

Benefits

  • Supports healthy mood and emotional wellbeing
  • Promotes joint comfort and mobility
  • Supports liver health and function
  • Assists in methylation processes
  • Helps maintain neurological health
  • Supports cellular regeneration

Common Forms

Enteric-coated tablets Capsules Oral supplements Injectable (medical use only)

Safety Notes

Generally well-tolerated when used as directed. May cause digestive upset in some individuals. Should not be combined with antidepressants without medical supervision due to potential serotonin syndrome risk. Not recommended for those with bipolar disorder as it may trigger manic episodes. Should be used cautiously in those with Parkinson's disease.

Related Products

Types of SAMe

SAMe Tosylate

The most common salt form of SAMe used in supplements, with good stability

Methylation compounds Methyl donors Research: Extensive
Available Forms:
Enteric-Coated SAMe Tosylate Buffered SAMe Tosylate

SAMe Butanedisulfonate

An alternative salt form of SAMe sometimes used in supplements and research

Methylation compounds Methyl donors Research: Moderate
Available Forms:
Standard SAMe Butanedisulfonate

SAMe Stable Salt Complexes

Enhanced stability formulations of SAMe using advanced salt combinations

Methylation compounds Methyl donors Research: Moderate
Available Forms:
SAMe MSB (Methionine S-Benzylthiuronium Salt) SAMe Tri-Salt Complex

Injectable SAMe

Pharmaceutical-grade SAMe for direct administration by healthcare professionals

Methylation compounds Methyl donors Research: Extensive
Available Forms:
Intravenous SAMe Intramuscular SAMe