β-Hydroxy β-Methylbutyrate (HMB)

A metabolite of leucine with anti-catabolic properties
Amino acids Essential amino acids Research: Extensive

Scientific Name

β-Hydroxy β-Methylbutyrate

Classifications

Function: anti-catabolic
Source: leucine-breakdown
Type: leucine-metabolite

Benefits

  • Supports muscle protein synthesis
  • Promotes muscle recovery after exercise
  • May help preserve lean muscle mass
  • Supports metabolic health
  • Functions as anti-caking agent in supplements
  • May support blood sugar regulation

Specific Properties

  • Derived from approximately 5% of leucine metabolism
  • Helps prevent muscle breakdown
  • May be more effective than leucine for certain goals
  • Particularly beneficial during caloric restriction
  • Used in body composition supplements
  • Typically requires 3g daily for optimal effects
  • Works through different pathway than creatine

Safety Notes

Generally recognized as safe when used as directed. Well-tolerated even at higher doses. May cause mild digestive discomfort in some individuals. Those with maple syrup urine disease should avoid leucine supplementation.

Related Products

Preparation Form

β-Hydroxy β-Methylbutyrate (HMB)

A preparation of Leucine Metabolites

Preparations of β-Hydroxy β-Methylbutyrate (HMB)

HMB Calcium

The calcium salt form of HMB, most commonly used in supplements

Research: Extensive
Most stable and researched form +4 more properties

HMB Free Acid

The free acid form of HMB with potentially faster absorption

Research: Moderate
Faster absorption than calcium salt +4 more properties