Berberine

A bioactive alkaloid compound found in several plants, with a bright yellow color, widely used in traditional Chinese and Ayurvedic medicine for its potential benefits on metabolic health and antimicrobial properties
Phytonutrients Alkaloids Research: Extensive

Scientific Name

Berberine (C20H18NO4+)

Also Known As

Berberine Berberine hydrochloride Berberine sulfate Berberine chloride

Benefits

  • Supports healthy blood glucose metabolism
  • May help maintain healthy cholesterol levels already within normal range
  • Supports cardiovascular health
  • Has antimicrobial properties
  • May support gastrointestinal health
  • Supports healthy inflammatory response

Common Forms

Hydrochloride salt Sulfate salt Plant extracts Capsules Tablets

Safety Notes

Generally well-tolerated when used as directed, but may cause digestive discomfort including constipation, diarrhea, or stomach upset. May interact with certain medications including blood thinners, some antibiotics, and medications metabolized by cytochrome P450 enzymes. May lower blood glucose, so caution is advised for those on diabetes medications. Not recommended during pregnancy or breastfeeding. Start with lower doses to assess tolerance. Consult healthcare practitioner before use, especially if taking medications or have a medical condition.

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Types of Berberine

Berberine Hydrochloride

The most common salt form of berberine used in supplements, known for better stability and absorption

Phytonutrients Alkaloids Research: Extensive

Berberine Sulfate

The sulfate salt form of berberine, used in some supplement formulations

Phytonutrients Alkaloids Research: Moderate

Natural Berberine

Berberine in its natural context within plant extracts, containing berberine alongside other plant compounds

Phytonutrients Alkaloids Research: Moderate